Reactive species generated by heme impair alveolar epithelial sodium channel function in acute respiratory distress syndrome

We previously reported that the highly reactive cell-free heme (CFH) is increased in the plasma of patients with chronic lung injury and causes pulmonary edema in animal model of acute respiratory distress syndrome (ARDS) post inhalation of halogen gas. However, the mechanisms by which CFH causes pu...

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Gepubliceerd in:Redox Biol
Hoofdauteurs: Aggarwal, Saurabh, Lazrak, Ahmed, Ahmad, Israr, Yu, Zhihong, Bryant, Ayesha, Mobley, James A., Ford, David A., Matalon, Sadis
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2020
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Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7276446/
https://ncbi.nlm.nih.gov/pubmed/32506040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101592
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