Reactive species generated by heme impair alveolar epithelial sodium channel function in acute respiratory distress syndrome

We previously reported that the highly reactive cell-free heme (CFH) is increased in the plasma of patients with chronic lung injury and causes pulmonary edema in animal model of acute respiratory distress syndrome (ARDS) post inhalation of halogen gas. However, the mechanisms by which CFH causes pu...

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Vydáno v:Redox Biol
Hlavní autoři: Aggarwal, Saurabh, Lazrak, Ahmed, Ahmad, Israr, Yu, Zhihong, Bryant, Ayesha, Mobley, James A., Ford, David A., Matalon, Sadis
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2020
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Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7276446/
https://ncbi.nlm.nih.gov/pubmed/32506040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101592
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