Reactive species generated by heme impair alveolar epithelial sodium channel function in acute respiratory distress syndrome

We previously reported that the highly reactive cell-free heme (CFH) is increased in the plasma of patients with chronic lung injury and causes pulmonary edema in animal model of acute respiratory distress syndrome (ARDS) post inhalation of halogen gas. However, the mechanisms by which CFH causes pu...

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Bibliographische Detailangaben
Veröffentlicht in:Redox Biol
Hauptverfasser: Aggarwal, Saurabh, Lazrak, Ahmed, Ahmad, Israr, Yu, Zhihong, Bryant, Ayesha, Mobley, James A., Ford, David A., Matalon, Sadis
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2020
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7276446/
https://ncbi.nlm.nih.gov/pubmed/32506040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101592
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