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Stringency of start codon selection modulates autoregulation of translation initiation factor eIF5

An AUG in an optimal nucleotide context is the preferred translation initiation site in eukaryotic cells. Interactions among translation initiation factors, including eIF1 and eIF5, govern start codon selection. Experiments described here showed that high intracellular eIF5 levels reduced the string...

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Bibliografiske detaljer
Main Authors: Loughran, Gary, Sachs, Matthew S., Atkins, John F., Ivanov, Ivaylo P.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326321/
https://ncbi.nlm.nih.gov/pubmed/22156057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1192
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