Stringency of start codon selection modulates autoregulation of translation initiation factor eIF5

An AUG in an optimal nucleotide context is the preferred translation initiation site in eukaryotic cells. Interactions among translation initiation factors, including eIF1 and eIF5, govern start codon selection. Experiments described here showed that high intracellular eIF5 levels reduced the string...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Loughran, Gary, Sachs, Matthew S., Atkins, John F., Ivanov, Ivaylo P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2012
Gaiak:
Gene Regulation, Chromatin and Epigenetics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326321/
https://ncbi.nlm.nih.gov/pubmed/22156057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1192
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