Stringency of start codon selection modulates autoregulation of translation initiation factor eIF5

An AUG in an optimal nucleotide context is the preferred translation initiation site in eukaryotic cells. Interactions among translation initiation factors, including eIF1 and eIF5, govern start codon selection. Experiments described here showed that high intracellular eIF5 levels reduced the string...

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Hlavní autoři: Loughran, Gary, Sachs, Matthew S., Atkins, John F., Ivanov, Ivaylo P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2012
Témata:
Gene Regulation, Chromatin and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326321/
https://ncbi.nlm.nih.gov/pubmed/22156057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1192
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