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Suppression of protein aggregation by chaperone modification of high molecular weight complexes
Protein misfolding and aggregation are associated with many neurodegenerative diseases, including Huntington’s disease. The cellular machinery for maintaining proteostasis includes molecular chaperones that facilitate protein folding and reduce proteotoxicity. Increasing the protein folding capacity...
Tallennettuna:
| Päätekijät: | , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Oxford University Press
2012
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3326252/ https://ncbi.nlm.nih.gov/pubmed/22396390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/aws022 |
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