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The molecular chaperones DNAJB6 and Hsp70 cooperate to suppress α-synuclein aggregation
A major hallmark of Parkinson’s disease (PD) is the presence of Lewy bodies (LBs) in certain neuronal tissues. LBs are protein-rich inclusions, in which α-synuclein (α-syn) is the most abundant protein. Since these inclusions are not present in healthy individuals, despite the high concentration of...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5567236/ https://ncbi.nlm.nih.gov/pubmed/28831037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08324-z |
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