Cooperative Assembly of Hsp70 Subdomain Clusters

[Image: see text] Many molecular chaperones exist as oligomeric complexes in their functional states, yet the physical determinants underlying such self-assembly behavior, as well as the role of oligomerization in the activity of molecular chaperones in inhibiting protein aggregation, have proven to...

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Veröffentlicht in:Biochemistry
Hauptverfasser: Wright, Maya A., Aprile, Francesco A., Bellaiche, Mathias M. J., Michaels, Thomas C. T., Müller, Thomas, Arosio, Paolo, Vendruscolo, Michele, Dobson, Christopher M., Knowles, Tuomas P. J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2018
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6202011/
https://ncbi.nlm.nih.gov/pubmed/29763298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00151
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