Á lódáil...

Sequential assistance of molecular chaperones and transient formation of covalent complexes during protein degradation from the ER

BACE457 is a recently identified pancreatic isoform of human β-secretase. We report that this membrane glycoprotein and its soluble variant are characterized by inefficient folding in the ER, leading to proteasome-mediated ER-associated degradation (ERAD). Dissection of the degradation process revea...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Main Authors: Molinari, Maurizio, Galli, Carmela, Piccaluga, Verena, Pieren, Michel, Paganetti, Paolo
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Rockefeller University Press 2002
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173128/
https://ncbi.nlm.nih.gov/pubmed/12119363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200204122
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!