Insulin Receptor Substrate 2 (IRS2)-Deficient Mice Show Sensorineural Hearing Loss That Is Delayed by Concomitant Protein Tyrosine Phosphatase 1B (PTP1B) Loss of Function

The insulin receptor substrate (IRS) proteins are key mediators of insulin and insulinlike growth factor 1 (IGF-1) signaling. Protein tyrosine phosphatase (PTP)-1B dephosphorylates and inactivates both insulin and IGF-1 receptors. IRS2-deficient mice present altered hepatic insulin signaling and β-c...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Murillo-Cuesta, Silvia, Camarero, Guadalupe, González-Rodríguez, Águeda, de la Rosa, Lourdes Rodríguez, Burks, Deborah J, Avendaño, Carlos, Valverde, Ángela M, Varela-Nieto, Isabel
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: ScholarOne 2011
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324951/
https://ncbi.nlm.nih.gov/pubmed/22160220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2011.00328
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