Insulin Receptor Substrate 2 (IRS2)-Deficient Mice Show Sensorineural Hearing Loss That Is Delayed by Concomitant Protein Tyrosine Phosphatase 1B (PTP1B) Loss of Function

The insulin receptor substrate (IRS) proteins are key mediators of insulin and insulinlike growth factor 1 (IGF-1) signaling. Protein tyrosine phosphatase (PTP)-1B dephosphorylates and inactivates both insulin and IGF-1 receptors. IRS2-deficient mice present altered hepatic insulin signaling and β-c...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Murillo-Cuesta, Silvia, Camarero, Guadalupe, González-Rodríguez, Águeda, de la Rosa, Lourdes Rodríguez, Burks, Deborah J, Avendaño, Carlos, Valverde, Ángela M, Varela-Nieto, Isabel
Formato: Artigo
Idioma:Inglês
Publicado em: ScholarOne 2011
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324951/
https://ncbi.nlm.nih.gov/pubmed/22160220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2011.00328
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
A carregar...

Registos relacionados