Protein Tyrosine Phosphatase 1B (PTP1B) Deficiency Accelerates Hepatic Regeneration in Mice

Protein tyrosine phosphatase 1B (PTP1B) is a key regulator of metabolism and cell growth by its ability to dephosphorylate tyrosine kinase receptors and modulate the intensity of their signaling cascades. Because liver regeneration involves tyrosine phosphorylation–mediated signaling, we investigate...

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Detalhes bibliográficos
Main Authors: Revuelta-Cervantes, Jesús, Mayoral, Rafael, Miranda, Soledad, González-Rodríguez, Águeda, Fernández, Margarita, Martín-Sanz, Paloma, Valverde, Ángela M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2011
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078461/
https://ncbi.nlm.nih.gov/pubmed/21406170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.12.020
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