Pivotal role of protein tyrosine phosphatase 1B (PTP1B) in the macrophage response to pro-inflammatory and anti-inflammatory challenge

Inhibition of protein tyrosine phosphatase 1B (PTP1B) has been suggested as an attractive target to improve insulin sensitivity in different cell types. In the present work, we have investigated the effect of PTP1B deficiency on the response of human and murine macrophages. Using in vitro and in viv...

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Detalhes bibliográficos
Main Authors: Través, P G, Pardo, V, Pimentel-Santillana, M, González-Rodríguez, Á, Mojena, M, Rico, D, Montenegro, Y, Calés, C, Martín-Sanz, P, Valverde, A M, Boscá, L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973223/
https://ncbi.nlm.nih.gov/pubmed/24625984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.90
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