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Structural basis of PIP(2) activation of the classical inward rectifier K(+) channel Kir2.2

The regulation of ion channel activity by specific lipid molecules is widely recognized as an integral component of electrical signaling in cells(1,2). In particular, phosphatidylinositol 4,5-bisphosphate (PIP(2)), a minor yet dynamic phospholipid component of cell membranes, is known to regulate ma...

詳細記述

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書誌詳細
主要な著者: Hansen, Scott B., Tao, Xiao, MacKinnon, Roderick
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324908/
https://ncbi.nlm.nih.gov/pubmed/21874019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10370
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