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Structural basis of PIP(2) activation of the classical inward rectifier K(+) channel Kir2.2
The regulation of ion channel activity by specific lipid molecules is widely recognized as an integral component of electrical signaling in cells(1,2). In particular, phosphatidylinositol 4,5-bisphosphate (PIP(2)), a minor yet dynamic phospholipid component of cell membranes, is known to regulate ma...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3324908/ https://ncbi.nlm.nih.gov/pubmed/21874019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10370 |
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