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Proteomic Candidate Biomarkers of Drug-Induced Nephrotoxicity in the Rat

Improved biomarkers of acute nephrotoxicity are coveted by the drug development industry, regulatory agencies, and clinicians. In an effort to identify such biomarkers, urinary peptide profiles of rats treated with two different nephrotoxins were investigated. 493 marker candidates were defined that...

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Bibliografische gegevens
Hoofdauteurs: Rouse, Rodney, Siwy, Justyna, Mullen, William, Mischak, Harald, Metzger, Jochen, Hanig, Joseph
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324487/
https://ncbi.nlm.nih.gov/pubmed/22509332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034606
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