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Proteomic Candidate Biomarkers of Drug-Induced Nephrotoxicity in the Rat

Improved biomarkers of acute nephrotoxicity are coveted by the drug development industry, regulatory agencies, and clinicians. In an effort to identify such biomarkers, urinary peptide profiles of rats treated with two different nephrotoxins were investigated. 493 marker candidates were defined that...

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Hlavní autoři: Rouse, Rodney, Siwy, Justyna, Mullen, William, Mischak, Harald, Metzger, Jochen, Hanig, Joseph
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324487/
https://ncbi.nlm.nih.gov/pubmed/22509332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034606
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