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Proteomic Candidate Biomarkers of Drug-Induced Nephrotoxicity in the Rat

Improved biomarkers of acute nephrotoxicity are coveted by the drug development industry, regulatory agencies, and clinicians. In an effort to identify such biomarkers, urinary peptide profiles of rats treated with two different nephrotoxins were investigated. 493 marker candidates were defined that...

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Detalhes bibliográficos
Main Authors: Rouse, Rodney, Siwy, Justyna, Mullen, William, Mischak, Harald, Metzger, Jochen, Hanig, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324487/
https://ncbi.nlm.nih.gov/pubmed/22509332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034606
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