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Proteomic Candidate Biomarkers of Drug-Induced Nephrotoxicity in the Rat

Improved biomarkers of acute nephrotoxicity are coveted by the drug development industry, regulatory agencies, and clinicians. In an effort to identify such biomarkers, urinary peptide profiles of rats treated with two different nephrotoxins were investigated. 493 marker candidates were defined that...

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Библиографические подробности
Главные авторы: Rouse, Rodney, Siwy, Justyna, Mullen, William, Mischak, Harald, Metzger, Jochen, Hanig, Joseph
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324487/
https://ncbi.nlm.nih.gov/pubmed/22509332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034606
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