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Proteomic Candidate Biomarkers of Drug-Induced Nephrotoxicity in the Rat
Improved biomarkers of acute nephrotoxicity are coveted by the drug development industry, regulatory agencies, and clinicians. In an effort to identify such biomarkers, urinary peptide profiles of rats treated with two different nephrotoxins were investigated. 493 marker candidates were defined that...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3324487/ https://ncbi.nlm.nih.gov/pubmed/22509332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034606 |
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