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Proteomic Candidate Biomarkers of Drug-Induced Nephrotoxicity in the Rat

Improved biomarkers of acute nephrotoxicity are coveted by the drug development industry, regulatory agencies, and clinicians. In an effort to identify such biomarkers, urinary peptide profiles of rats treated with two different nephrotoxins were investigated. 493 marker candidates were defined that...

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Detaylı Bibliyografya
Asıl Yazarlar: Rouse, Rodney, Siwy, Justyna, Mullen, William, Mischak, Harald, Metzger, Jochen, Hanig, Joseph
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324487/
https://ncbi.nlm.nih.gov/pubmed/22509332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034606
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