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Reactive polymer enables efficient in vivo bioorthogonal chemistry

There has been intense interest in the development of selective bioorthogonal reactions or “click” chemistry that can proceed in live animals. Until now however, most reactions still require vast surpluses of reactants because of steep temporal and spatial concentration gradients. Using computationa...

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Autors principals: Devaraj, Neal K., Thurber, Greg M., Keliher, Edmund J., Marinelli, Brett, Weissleder, Ralph
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324005/
https://ncbi.nlm.nih.gov/pubmed/22411831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1113466109
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