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Reactive polymer enables efficient in vivo bioorthogonal chemistry

There has been intense interest in the development of selective bioorthogonal reactions or “click” chemistry that can proceed in live animals. Until now however, most reactions still require vast surpluses of reactants because of steep temporal and spatial concentration gradients. Using computationa...

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Bibliografiske detaljer
Main Authors: Devaraj, Neal K., Thurber, Greg M., Keliher, Edmund J., Marinelli, Brett, Weissleder, Ralph
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324005/
https://ncbi.nlm.nih.gov/pubmed/22411831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1113466109
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