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Reactive polymer enables efficient in vivo bioorthogonal chemistry

There has been intense interest in the development of selective bioorthogonal reactions or “click” chemistry that can proceed in live animals. Until now however, most reactions still require vast surpluses of reactants because of steep temporal and spatial concentration gradients. Using computationa...

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Hlavní autoři: Devaraj, Neal K., Thurber, Greg M., Keliher, Edmund J., Marinelli, Brett, Weissleder, Ralph
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324005/
https://ncbi.nlm.nih.gov/pubmed/22411831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1113466109
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