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Reactive polymer enables efficient in vivo bioorthogonal chemistry

There has been intense interest in the development of selective bioorthogonal reactions or “click” chemistry that can proceed in live animals. Until now however, most reactions still require vast surpluses of reactants because of steep temporal and spatial concentration gradients. Using computationa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Devaraj, Neal K., Thurber, Greg M., Keliher, Edmund J., Marinelli, Brett, Weissleder, Ralph
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324005/
https://ncbi.nlm.nih.gov/pubmed/22411831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1113466109
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