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Selective CDK inhibitor limits neuroinflammation and progressive neurodegeneration after brain trauma
Traumatic brain injury (TBI) induces secondary injury mechanisms, including cell-cycle activation (CCA), which lead to neuronal cell death, microglial activation, and neurologic dysfunction. Here, we show progressive neurodegeneration associated with microglial activation after TBI induced by contro...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3323296/ https://ncbi.nlm.nih.gov/pubmed/21829212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2011.117 |
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