Selective CDK inhibitor limits neuroinflammation and progressive neurodegeneration after brain trauma

Traumatic brain injury (TBI) induces secondary injury mechanisms, including cell-cycle activation (CCA), which lead to neuronal cell death, microglial activation, and neurologic dysfunction. Here, we show progressive neurodegeneration associated with microglial activation after TBI induced by contro...

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Bibliografske podrobnosti
Main Authors: Kabadi, Shruti V, Stoica, Bogdan A, Byrnes, Kimberly R, Hanscom, Marie, Loane, David J, Faden, Alan I
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2012
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3323296/
https://ncbi.nlm.nih.gov/pubmed/21829212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2011.117
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