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Direct Observation of Strand Passage by DNA-Topoisomerase and Its Limited Processivity
Type-II DNA topoisomerases resolve DNA entanglements such as supercoils, knots and catenanes by passing one segment of DNA duplex through a transient enzyme-bridged double-stranded break in another segment. The ATP-dependent passage reaction has previously been demonstrated at the single-molecule le...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3322154/ https://ncbi.nlm.nih.gov/pubmed/22496876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034920 |
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