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Retroviral Integrations in Gene Therapy Trials
γ-Retroviral and lentiviral vectors allow the permanent integration of a therapeutic transgene in target cells and have provided in the last decade a delivery platform for several successful gene therapy (GT) clinical approaches. However, the occurrence of adverse events due to insertional mutagenes...
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| Prif Awduron: | , , |
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| Fformat: | Artigo |
| Iaith: | Inglês |
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Nature Publishing Group
2012
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| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3321603/ https://ncbi.nlm.nih.gov/pubmed/22252453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.289 |
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