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Integration Site and Clonal Expansion in Human Chronic Retroviral Infection and Gene Therapy

Retroviral vectors have been successfully used therapeutically to restore expression of genes in a range of single-gene diseases, including several primary immunodeficiency disorders. Although clinical trials have shown remarkable results, there have also been a number of severe adverse events invol...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Niederer, Heather A., Bangham, Charles R. M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246213/
https://ncbi.nlm.nih.gov/pubmed/25365582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v6114140
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