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Retroviral integration and human gene therapy

Long-term correction of genetic diseases requires permanent integration of therapeutic genes into chromosomes of affected cells. Retroviral vectors are the most widely used delivery vehicles because of their efficiency and precision of integration. However, retroviral integration can take place at a...

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Détails bibliographiques
Auteur principal: Bushman, Frederic D.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1934602/
https://ncbi.nlm.nih.gov/pubmed/17671645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32949
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