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Retroviral integration and human gene therapy

Long-term correction of genetic diseases requires permanent integration of therapeutic genes into chromosomes of affected cells. Retroviral vectors are the most widely used delivery vehicles because of their efficiency and precision of integration. However, retroviral integration can take place at a...

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Detalles Bibliográficos
Autor Principal: Bushman, Frederic D.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2007
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1934602/
https://ncbi.nlm.nih.gov/pubmed/17671645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32949
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