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Present and Future of EGFR Inhibitors for Head and Neck Squamous Cell Cancer

Although EGFR is expressed at high levels in head and neck squamous cell carcinomas (HNSCCs) and mutations are extremely rare, monotherapy with EGFR inhibitors has shown limited success. The PI3kinase/Akt pathway is responsible for cellular survival, and inhibition of phosphatidylinositol (PI) synth...

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Sonraí Bibleagrafaíochta
Main Authors: Baba, Yuh, Fujii, Masato, Tokumaru, Yutaka, Kato, Yasumasa
Formáid: Artigo
Teanga:Inglês
Foilsithe: Hindawi Publishing Corporation 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321461/
https://ncbi.nlm.nih.gov/pubmed/22545054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/986725
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