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Present and Future of EGFR Inhibitors for Head and Neck Squamous Cell Cancer

Although EGFR is expressed at high levels in head and neck squamous cell carcinomas (HNSCCs) and mutations are extremely rare, monotherapy with EGFR inhibitors has shown limited success. The PI3kinase/Akt pathway is responsible for cellular survival, and inhibition of phosphatidylinositol (PI) synth...

詳細記述

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書誌詳細
主要な著者: Baba, Yuh, Fujii, Masato, Tokumaru, Yutaka, Kato, Yasumasa
フォーマット: Artigo
言語:Inglês
出版事項: Hindawi Publishing Corporation 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321461/
https://ncbi.nlm.nih.gov/pubmed/22545054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/986725
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