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Deguelin Potentiates Apoptotic Activity of an EGFR Tyrosine Kinase Inhibitor (AG1478) in PIK3CA-Mutated Head and Neck Squamous Cell Carcinoma

Head and neck squamous cell carcinoma (HNSCC) is known to be intrinsically resistant to inhibitors for epidermal growth factor receptor (EGFR). Until now, clinical outcomes for HNSCC using EGFR inhibitors as single agents have yielded disappointing results. Here, we aimed to study whether combinator...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Baba, Yuh, Maeda, Toyonobu, Suzuki, Atsuko, Takada, Satoshi, Fujii, Masato, Kato, Yasumasa
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5343798/
https://ncbi.nlm.nih.gov/pubmed/28134774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18020262
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