Deguelin Induces Apoptosis by Targeting Both EGFR-Akt and IGF1R-Akt Pathways in Head and Neck Squamous Cell Cancer Cell Lines

Deguelin, a rotenoid compound from the African plant Mundulea sericea (Leguminosae), has been shown to possess antitumor activities but the exact role for the growth factor receptor mediated signaling pathway in head and neck squamous cell carcinoma (HNSCC) is currently still unclear. In the present...

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Bibliografiske detaljer
Udgivet i:Biomed Res Int
Main Authors: Baba, Yuh, Fujii, Masato, Maeda, Toyonobu, Suzuki, Atsuko, Yuzawa, Satoshi, Kato, Yasumasa
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449895/
https://ncbi.nlm.nih.gov/pubmed/26075254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/657179
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