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Deguelin Induces Apoptosis by Targeting Both EGFR-Akt and IGF1R-Akt Pathways in Head and Neck Squamous Cell Cancer Cell Lines

Deguelin, a rotenoid compound from the African plant Mundulea sericea (Leguminosae), has been shown to possess antitumor activities but the exact role for the growth factor receptor mediated signaling pathway in head and neck squamous cell carcinoma (HNSCC) is currently still unclear. In the present...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Baba, Yuh, Fujii, Masato, Maeda, Toyonobu, Suzuki, Atsuko, Yuzawa, Satoshi, Kato, Yasumasa
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449895/
https://ncbi.nlm.nih.gov/pubmed/26075254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/657179
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