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Deguelin Induces Apoptosis by Targeting Both EGFR-Akt and IGF1R-Akt Pathways in Head and Neck Squamous Cell Cancer Cell Lines

Deguelin, a rotenoid compound from the African plant Mundulea sericea (Leguminosae), has been shown to possess antitumor activities but the exact role for the growth factor receptor mediated signaling pathway in head and neck squamous cell carcinoma (HNSCC) is currently still unclear. In the present...

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Dettagli Bibliografici
Pubblicato in:Biomed Res Int
Autori principali: Baba, Yuh, Fujii, Masato, Maeda, Toyonobu, Suzuki, Atsuko, Yuzawa, Satoshi, Kato, Yasumasa
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449895/
https://ncbi.nlm.nih.gov/pubmed/26075254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/657179
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