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Cell cycle control of Wnt/β-catenin signalling by conductin/axin2 through CDC20
Wnt/β-catenin signalling regulates cell proliferation by modulating the cell cycle and is negatively regulated by conductin/axin2/axil. We show that conductin levels peak at G2/M followed by a rapid decline during return to G1. In line with this, Wnt/β-catenin target genes are low at G2/M and high a...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3321148/ https://ncbi.nlm.nih.gov/pubmed/22322943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2012.12 |
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