Intestinal Cell Kinase (ICK) Promotes Activation of mTOR Complex 1 (mTORC1) through Phosphorylation of Raptor Thr-908

Intestinal cell kinase (ICK), named after its cloning origin, the intestine, is actually a ubiquitously expressed and highly conserved serine/threonine protein kinase. Recently we reported that ICK supports cell proliferation and G(1) cell cycle progression. ICK deficiency significantly disrupted th...

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Detalhes bibliográficos
Main Authors: Wu, Di, Chapman, Jessica R., Wang, Lifu, Harris, Thurl E., Shabanowitz, Jeffrey, Hunt, Donald F., Fu, Zheng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321000/
https://ncbi.nlm.nih.gov/pubmed/22356909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.302117
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