טוען...
Local unfolding of Cu, Zn Superoxide Dismutase monomer determines the morphology of fibrillar aggregates
Aggregation of Cu, Zn Superoxide Dismutase (SOD1) is often found in Amyotrophic Lateral Sclerosis (ALS) patients. The fibrillar aggregates formed by wildtype and various disease-associated mutants have recently been found to have distinct cores and morphologies. Previous computational and experiment...
שמור ב:
| Main Authors: | , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2011
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3320695/ https://ncbi.nlm.nih.gov/pubmed/22210350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.12.029 |
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