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A seeded propagation of Cu, Zn-superoxide dismutase aggregates in amyotrophic lateral sclerosis

Abnormal accumulation of protein inclusions in motor neurons has been known as a major pathological change in amyotrophic lateral sclerosis (ALS). Increasing numbers of proteins including mutant Cu, Zn-superoxide dismutase (SOD1) have been identified as constituents of pathological inclusions in a f...

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Detalhes bibliográficos
Main Authors: Ogawa, Mariko, Furukawa, Yoshiaki
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3957682/
https://ncbi.nlm.nih.gov/pubmed/24672430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00083
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