Comparative Analysis of Mycobacterium tuberculosis pe and ppe Genes Reveals High Sequence Variation and an Apparent Absence of Selective Constraints

Mycobacterium tuberculosis complex (MTBC) genomes contain 2 large gene families termed pe and ppe. The function of pe/ppe proteins remains enigmatic but studies suggest that they are secreted or cell surface associated and are involved in bacterial virulence. Previous studies have also shown that so...

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Bibliografski detalji
Glavni autori: McEvoy, Christopher R. E., Cloete, Ruben, Müller, Borna, Schürch, Anita C., van Helden, Paul D., Gagneux, Sebastien, Warren, Robin M., Gey van Pittius, Nicolaas C.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319526/
https://ncbi.nlm.nih.gov/pubmed/22496726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030593
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