Recombination in pe/ppe genes contributes to genetic variation in Mycobacterium tuberculosis lineages

BACKGROUND: Approximately 10 % of the Mycobacterium tuberculosis genome is made up of two families of genes that are poorly characterized due to their high GC content and highly repetitive nature. The PE and PPE families are typified by their highly conserved N-terminal domains that incorporate prol...

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Pubblicato in:BMC Genomics
Autori principali: Phelan, Jody E., Coll, Francesc, Bergval, Indra, Anthony, Richard M., Warren, Rob, Sampson, Samantha L., Gey van Pittius, Nicolaas C., Glynn, Judith R., Crampin, Amelia C., Alves, Adriana, Bessa, Theolis Barbosa, Campino, Susana, Dheda, Keertan, Grandjean, Louis, Hasan, Rumina, Hasan, Zahra, Miranda, Anabela, Moore, David, Panaiotov, Stefan, Perdigao, Joao, Portugal, Isabel, Sheen, Patricia, de Oliveira Sousa, Erivelton, Streicher, Elizabeth M., van Helden, Paul D., Viveiros, Miguel, Hibberd, Martin L., Pain, Arnab, McNerney, Ruth, Clark, Taane G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770551/
https://ncbi.nlm.nih.gov/pubmed/26923687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2467-y
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