Evidence for a rapid rate of molecular evolution at the hypervariable and immunogenic Mycobacterium tuberculosis PPE38 gene region

BACKGROUND: PPE38 (Rv2352c) is a member of the large PPE gene family of Mycobacterium tuberculosis and related mycobacteria. The function of PPE proteins is unknown but evidence suggests that many are cell-surface associated and recognised by the host immune system. Previous studies targeting other...

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Bibliographic Details
Main Authors: McEvoy, Christopher RE, van Helden, Paul D, Warren, Robin M, van Pittius, Nicolaas C Gey
Format: Artigo
Language:Inglês
Published: BioMed Central 2009
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2758852/
https://ncbi.nlm.nih.gov/pubmed/19769792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-9-237
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