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Evolution and expansion of the Mycobacterium tuberculosis PE and PPE multigene families and their association with the duplication of the ESAT-6 (esx) gene cluster regions

BACKGROUND: The PE and PPE multigene families of Mycobacterium tuberculosis comprise about 10% of the coding potential of the genome. The function of the proteins encoded by these large gene families remains unknown, although they have been proposed to be involved in antigenic variation and disease...

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Autori principali: Gey van Pittius, Nicolaas C, Sampson, Samantha L, Lee, Hyeyoung, Kim, Yeun, van Helden, Paul D, Warren, Robin M
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1660551/
https://ncbi.nlm.nih.gov/pubmed/17105670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-6-95
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