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Targeting Eph Receptors with Peptides and Small Molecules: Progress and Challenges
The Eph receptors are a large family of receptor tyrosine kinases. Their kinase activity and downstream signaling ability are stimulated by the binding of cell surface-associated ligands, the ephrins. The ensuing signals are bidirectional because the ephrins can also transduce signals (known as reve...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3319464/ https://ncbi.nlm.nih.gov/pubmed/22044885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2011.10.023 |
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