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Targeting Eph Receptors with Peptides and Small Molecules: Progress and Challenges

The Eph receptors are a large family of receptor tyrosine kinases. Their kinase activity and downstream signaling ability are stimulated by the binding of cell surface-associated ligands, the ephrins. The ensuing signals are bidirectional because the ephrins can also transduce signals (known as reve...

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Hlavní autoři: Noberini, Roberta, Lamberto, Ilaria, Pasquale, Elena B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319464/
https://ncbi.nlm.nih.gov/pubmed/22044885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2011.10.023
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