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Protein kinase A can block EphA2 receptor–mediated cell repulsion by increasing EphA2 S897 phosphorylation

The EphA2 receptor tyrosine kinase plays key roles in tissue homeostasis and disease processes such as cancer, pathological angiogenesis, and inflammation through two distinct signaling mechanisms. EphA2 “canonical” signaling involves ephrin-A ligand binding, tyrosine autophosphorylation, and kinase...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Barquilla, Antonio, Lamberto, Ilaria, Noberini, Roberta, Heynen-Genel, Susanne, Brill, Laurence M., Pasquale, Elena B.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007095/
https://ncbi.nlm.nih.gov/pubmed/27385333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-01-0048
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