PEGylation Potentiates the Effectiveness of an Antagonistic Peptide That Targets the EphB4 Receptor with Nanomolar Affinity

The EphB4 receptor tyrosine kinase together with its preferred ligand, ephrin-B2, regulates a variety of physiological and pathological processes, including tumor progression, pathological forms of angiogenesis, cardiomyocyte differentiation and bone remodeling. We previously reported the identifica...

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Bibliografiske detaljer
Main Authors: Noberini, Roberta, Mitra, Sayantan, Salvucci, Ombretta, Valencia, Fatima, Duggineni, Srinivas, Prigozhina, Natalie, Wei, Ke, Tosato, Giovanna, Huang, Ziwei, Pasquale, Elena B.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237458/
https://ncbi.nlm.nih.gov/pubmed/22194865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028611
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