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An enzyme-coupled continuous fluorescence assay for farnesyl diphosphate synthases
Farnesyl diphosphate synthase (FDPS) catalyzes the conversion of isopentenyl diphosphate and dimethylallyl diphosphate to farnesyl diphosphate, a crucial metabolic intermediate in the synthesis of cholesterol, ubiquinone and prenylated proteins; consequently, much effort has gone into developing inh...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3319381/ https://ncbi.nlm.nih.gov/pubmed/22085443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2011.10.038 |
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