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An enzyme-coupled continuous fluorescence assay for farnesyl diphosphate synthases

Farnesyl diphosphate synthase (FDPS) catalyzes the conversion of isopentenyl diphosphate and dimethylallyl diphosphate to farnesyl diphosphate, a crucial metabolic intermediate in the synthesis of cholesterol, ubiquinone and prenylated proteins; consequently, much effort has gone into developing inh...

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Detalles Bibliográficos
Main Authors: Dozier, Jonathan K, Distefano, Mark D
Formato: Artigo
Idioma:Inglês
Publicado: 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319381/
https://ncbi.nlm.nih.gov/pubmed/22085443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2011.10.038
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