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Synthesis and Evaluation of Chlorinated Substrate Analogues for Farnesyl Diphosphate Synthase

Substrate analogues for isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), where the C3 methyl groups were replaced by chlorine, were synthesized and evaluated as substrates for avian farnesyl diphosphate synthase (FPPase). The IPP analogue (3-ClIPP) was a co-substrate when incubat...

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Bibliografiska uppgifter
Huvudupphovsmän: Heaps, Nicole A., Poulter, C. Dale
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055917/
https://ncbi.nlm.nih.gov/pubmed/21344952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo1024305
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