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Synthesis and Evaluation of Chlorinated Substrate Analogues for Farnesyl Diphosphate Synthase
Substrate analogues for isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), where the C3 methyl groups were replaced by chlorine, were synthesized and evaluated as substrates for avian farnesyl diphosphate synthase (FPPase). The IPP analogue (3-ClIPP) was a co-substrate when incubat...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3055917/ https://ncbi.nlm.nih.gov/pubmed/21344952 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo1024305 |
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