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Farnesyl Diphosphate Synthase: The Art of Compromise between Substrate Selectivity and Stereoselectivity
Farnesyl diphosphate (FPP) synthase catalyzes the consecutive head-to-tail condensations of isopentenyl diphosphate (IPP, C(5)) with dimethylallyl diphosphate (DMAPP, C(5)) and geranyl diphosphate (GPP, C(10)) to give (E,E)-FPP (C(15)). The enzyme belongs to a genetically distinct family of chain el...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2516916/ https://ncbi.nlm.nih.gov/pubmed/17147392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja065573b |
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