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Farnesyl Diphosphate Synthase: The Art of Compromise between Substrate Selectivity and Stereoselectivity

Farnesyl diphosphate (FPP) synthase catalyzes the consecutive head-to-tail condensations of isopentenyl diphosphate (IPP, C(5)) with dimethylallyl diphosphate (DMAPP, C(5)) and geranyl diphosphate (GPP, C(10)) to give (E,E)-FPP (C(15)). The enzyme belongs to a genetically distinct family of chain el...

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Autori principali: Thulasiram, Hirekodathakallu V., Poulter, C. Dale
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2516916/
https://ncbi.nlm.nih.gov/pubmed/17147392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja065573b
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